Research Database

8 results for "Osteoarthritis Initiative"

The Role of Cohabitating Partner and Relationship Characteristics on Physical Activity among Individuals with Osteoarthritis

  • Published on July 15, 2019

Background Most individuals with knee or hip osteoarthritis do not meet recommendations for physical activity. The Social Cognitive Theory suggests that the social environment (e.g., spouses/partners) may influence the physical activity of individuals with osteoarthritis. The purpose of this study was to examine whether the physical activity of ...


Factors associated with articular cartilage T2 relaxation time in uninjured individuals

  • Published on April 27, 2019

Purpose Mechanical loading during physical activity promotes synthesis of proteoglycans and collagen in the extracellular matrix to maintain normal organization of cartilage. In healthy individuals, greater knee joint loading is associated with thicker articular cartilage. T2 relaxation time is a quantitative magnetic resonance imaging (MRI) method that can be used ...




Minimum performance on clinical tests of physical function to predict walking 6000 steps/day in knee osteoarthritis: An observational study.

  • Published on Oct 17, 2017

Objective: Evidence of physical function difficulties, such as difficulty rising from a chair, may limit daily walking for people with knee osteoarthritis (OA). The purpose of this study was to identify minimum performance thresholds on clinical tests of physical function predictive to walk ≥6000 steps/day. This benchmark is known to ...


The association of the neighborhood built environment with objectively measured physical activity in older adults with and without lower limb osteoarthritis

  • Published on Aug 3, 2016

Background: This study examined the associations of objectively measured neighborhood built environment characteristics with objectively measured physical activity (PA) in older people with and without lower limb osteoarthritis (LLOA), and assessed whether these relationships differ between both groups. Methods: Data from the Dutch component of the European Project on OSteoArthritis ...


Association of Physical Activity Measured by Accelerometer, Knee Joint Abnormalities, and Cartilage T2 Measurements Obtained From 3T Magnetic Resonance Imaging: Data From the Osteoarthritis Initiative

  • Published on Sep 2015

Objective: To study the cross-sectional association between physical activity measured with an accelerometer, structural knee abnormalities, and cartilage T2 values assessed with 3T magnetic resonance imaging (MRI). Methods: We included 274 subjects from the Osteoarthritis Initiative cohort without definite radiographic osteoarthritis (Kellgren/Lawrence grades 0 and 1) and with at most mild pain, ...


Objectively Measured Physical Activity and Symptoms Change in Knee Osteoarthritis

  • Published on Feb. 2, 2016

Objective: The study objective was to quantify the association between daily physical activity measured by accelerometer and 1-year changes in symptoms among people with knee osteoarthritis. Methods: Participants from the Osteoarthritis Initiative had knee radiographs and physical activity assessed using GT1M ActiGraph (Pensacola, FL) uniaxial accelerometers at the 48-month ...