Research Database

35 results for "CNS disorders"


Usability of a daily mHealth application designed to address mobility, speech and dexterity in Parkinson’s disease

  • Published on April 18, 2019

Aim: This study investigated the usability of a mobile health (mHealth) smartphone application to treat gait, speech and dexterity in people with Parkinson's disease. Methods: Participants either used an mHealth application (intervention) or maintained their normal routine (control) for 12 weeks and were evaluated at baseline and post-test time points for ...



Changing physical activity behavior for people with multiple sclerosis: protocol of a randomized controlled feasibility trial (iStep-MS)

  • Published on Nov 15, 2017

Introduction: Although physical activity may reduce disease burden, fatigue and disability, and improve quality of life among people with multiple sclerosis (MS), many people with MS are physically inactive and spend significant time in sedentary behavior. Behavior change interventions may assist people with MS to increase physical activity and reduce ...


Low physical activity as a key differentiating factor in the potential high-risk profile for depressive symptoms in older adults

  • Published on Sep 2017

Background: The identification of potential high-risk groups for depression is of importance. The purpose of the present study was to identify high-risk profiles for depressive symptoms in older individuals, with a focus on functional performance. Methods: The population-based Healthy Ageing Initiative included 2,084 community-dwelling individuals (49% women) aged 70. Explorative cluster analysis was ...



Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013

  • Published on Aug 9, 2016

Objective: To quantify the dose-response associations between total physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events. Design: Systematic review and Bayesian dose-response meta-analysis. Data Sources: PubMed and Embase from 1980 to 27 February 2016, and references from relevant systematic reviews. Data from the Study ...


Remote Physical Activity Monitoring in Neurological Disease: A Systematic Review

  • Published on April 28, 2016

Objective: To perform a systematic review of studies using remote physical activity monitoring in neurological diseases, highlighting advances and determining gaps. Methods: Studies were systematically identified in PubMed/MEDLINE, CINAHL and SCOPUS from January 2004 to December 2014 that monitored physical activity for 24 hours in adults with neurological diseases. Studies that measured ...



Mobility disability and the pattern of accelerometer-derived sedentary and physical activity behaviors in people with multiple sclerosis

  • Published on Apr 1, 2016

Objective: Low physical activity and high sedentary behavior levels are major concerns in persons with multiple sclerosis (MS) and these differ depending on the level of mobility disability. However, the manner in which daily activity is accumulated is currently unknown in this population. Methods: A secondary analysis was performed on ...