Research Database

47 results for "Clinical research"

Relationship between objectively measured physical activity and cardiovascular aging in the general population – The EVIDENT trial

  • Published on Jan. 24, 2014

Background Aging has been associated with an increase in arterial stiffness. We analyzed the relationship between regular physical activity and cardiovascular aging evaluated by the radial augmentation index (rAIx), ambulatory arterial stiffness index (AASI), pulse pressure (PP) and heart age in subjects without atherosclerotic disease. Methods A cross-sectional study was ...



Sedentary time and markers of chronic low-grade inflammation in a high risk population

  • Published on Oct. 29, 2013

Background Sedentary behaviour has been identified as a distinct risk factor for several health outcomes. Nevertheless, little research has been conducted into the underlying mechanisms driving these observations. This study aimed to investigate the association of objectively measured sedentary time and breaks in sedentary time with markers of chronic low-grade ...


Daily physical activity in ankylosing spondylitis: validity and reliability of the IPAQ and SQUASH and the relation with clinical assessments

  • Published on Aug. 23, 2013

Introduction The aim of this study was to investigate the construct validity and test-retest reliability of the International Physical Activity Questionnaire (IPAQ; long form) and the Short QUestionnaire to Assess Health-enhancing physical activity (SQUASH) and to investigate the relation between daily physical activity and clinical assessments in patients with ankylosing ...


Insulin secretion and its association with physical activity, fitness and screen time in children

  • Published on Oct. 16, 2013

Objective To determine the independent associations of moderate to vigorous physical activity (MVPA), fitness, screen time, and adiposity with insulin secretion in children. Design and Methods Caucasian youth (n = 423/630), 8-10 years old, with at least one obese biological parent, were studied (QUALITY cohort). Insulin secretion was measured using HOMA2-%...


Factors Associated with Sedentary Lifestyle of Hospitalized Patients Not Restricted to Bed

  • Added on October 30, 2013

Introduction The prolonged length of stay on the bed is related to the development of musculoskeletal and respiratory disorders. Therefore, the investigation of the level of physical activity and to verifying which factors are associated with the physical activity level in hospitalized patients might be important for future strategies to ...


A Longitudinal Study Evaluating the Effect of Exacerbations on Physical Activity in Patients with COPD

  • Published on Sept. 20, 2013

Background Physical inactivity is common in stable COPD and independently predicts poor outcomes. Longitudinal assessments of physical activity in outpatients with COPD, covering periods of stability and exacerbations, have not been evaluated previously. Methods Patients with clinically-stable COPD and a history of 2 or more clinical exacerbations in the preceding 12 months ...


Annual recollection of exacerbations in patients with COPD: Impact on physical activity

  • Presented on Sept. 9, 2013

Rationale The number of exacerbations in the previous year has shown to be the best predictor of new exacerbations. The ability to recall exacerbations may lead to misclassification of patients and may have consequences on patients’ phenotype. Methods 47 patients with COPD (FEV1 65±21%pred) reported on a monthly basis all health ...


Agreement of classification of COPD patients’ physical activity with two activity monitors

  • Presented on Sept. 8, 2013

Rationale It is unclear whether different activity monitors provide similar classification of physical activity (PA) in patients with COPD. Aim To test whether similar PA classification of patients would be obtained when using 2 valid activity monitors. Methods We assessed PA for 4 weeks with Actigraph [(ACT: Steps and vector magnitude units (...


Comparative Effectiveness of Afterschool Programs to Increase Physical Activity

  • Added on August 2, 2013

Background: We conducted a comparative effectiveness analysis to evaluate the difference in the amount of physical activity children engaged in when enrolled in a physical activity-enhanced after-school program (ASP) based in a community recreation center versus a standard school-based ASP. Methods: The study was a natural experiment with 54 elementary school ...