Research Database

71 results for "Cardiovascular Disease"

Concurrent Validity of Daily Activity Data From Medtronic ICD/CRT Devices and the Actigraph GT3X Triaxial Accelerometer: A Pilot Study

  • Published on Jan 2017

Purpose: The purpose of this pilot study was to examine the concurrent validity of daily activity data from Medtronic implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT) devices and the Actigraph GT3X triaxial accelerometer in patients with heart failure (HF). Methods: Analysis of the first 16 subjects with HF ...


A Pilot Characterization of the Human Chronobiome

  • Published on Dec 07, 2017

Abstract Physiological function, disease expression and drug effects vary by time-of-day. Clock disruption in mice results in cardio-metabolic, immunological and neurological dysfunction; circadian misalignment using forced desynchrony increases cardiovascular risk factors in humans. Here we integrated data from remote sensors, physiological and multi-omics analyses to assess the feasibility of detecting ...


Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial

  • Added on August 30, 2017

Background: Findings from the Look AHEAD trial showed no significant reductions in the primary outcome of cardiovascular disease incidence in adults with type 2 diabetes randomly assigned to an intensive lifestyle intervention for weight loss compared with those randomly assigned to diabetes support and education (control). We examined whether the incidence ...


Sedentary Time, Cardiorespiratory Fitness, and Cardiovascular Risk Factor Clustering in Older Adults–the Generation 100 Study

  • Published on Oct 2016

Objective: To determine whether meeting physical activity (PA) recommendations and/or having high age-specific cardiorespiratory fitness (CRF) attenuate the adverse effect of prolonged sedentary time on cardiovascular risk factor (CV-RF) clustering in older adults. Patients and Methods: We conducted a cross-sectional study of Norwegian women (495) and men (379) aged 70 to 77 years ...


Sedentary Behavior, Physical Activity, and Abdominal Adipose Tissue Deposition

  • Published on Mar 2017

Purpose: We examined whether sedentary lifestyle habits and physical activity level are associated with abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intermuscular adipose tissue (IMAT), and liver attenuation, independently of one another and potential confounders. Methods: This study analyzed 3010 African American and Caucasian men and women, 42–59 yr old, ...



Estimating energy expenditure during outdoor level walking using Global Positioning System or accelerometry in patients with peripheral artery disease

  • Published on Jun 21, 2017

Introduction. Estimating energy expenditure (EE) related to outdoor walking capacity in peripheral artery disease (PAD) patients could allow a better standardization of the assessment of their limitations during free-living outdoor walking. However, there is no data regarding the accuracy of ambulatory methods to perform such estimations. Our aim was to ...


Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013

  • Published on Aug 9, 2016

Objective: To quantify the dose-response associations between total physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events. Design: Systematic review and Bayesian dose-response meta-analysis. Data Sources: PubMed and Embase from 1980 to 27 February 2016, and references from relevant systematic reviews. Data from the Study ...


Correlates of objectively measured physical activity in cardiac patients.

  • Published on 6 Oct, 2014

Cardiac patients would benefit from increasing their physical activity (PA) levels. Understanding of factors that influence cardiac patients' PA participation would benefit the development of effective interventions. Therefore, the purpose of this study was to determine correlates of objectively-measured PA in cardiac patients. Participants were 65 cardiac patients (74% male, 95% white), age 58.6±10.6 ...


Physical activity in hypertrophic cardiomyopathy: prevalence of inactivity and perceived barriers

  • Published on Jul 20, 2016

Objectives: This study aimed to determine the prevalence of physical inactivity and perceived barriers to physical activity among individuals with hypertrophic cardiomyopathy (HCM), and to determine potential demographic, clinical and health-related factors influencing likelihood of meeting physical activity guidelines. Methods: This was a cross-sectional study of consecutive patients (n=198) with ...