Background: Larger brain volumes are often associated with more free-living physical activity (PA) in cognitively normal older adults. Yet, whether greater brain volumes are associated with more favorable (less fragmented) PA patterns, and whether this association is stronger than with total PA, remains unknown. Methods: Brain magnetic resonance imaging and ...
Background: Individuals with Down syndrome (DS) are less physically active than the general population, but limited data on objective physical activity patterns in adults with DS are available. Methods: Free-living physical activity was measured by waist-worn accelerometry in adults with DS from 2018 to 2020. Data were analysed using descriptive statistics, bivariate ...
Introduction: Although numerous activity trackers have been validated in healthy populations, validation is lacking in chronic heart failure patients who normally walk at a slower pace, making it difficult for researchers and clinicians to implement activity monitors during physical activity interventions. Methods: Six consumer-level activity monitors were validated in a 3...
Objective Chronic obstructive pulmonary disease (COPD) is mainly treated pharmaceutically with bronchodilators. The purpose of this study was to evaluate the clinical benefits of two-times-per-day aclidinium bromide (Acli-BID) compared with once-a-day tiotropium bromide hydrate (Tio-QD) in patients with COPD. Design This study was a multicentre, open-label, randomised study. Setting Fourcentres ...
Background The fat mass and obesity-associated gene (FTO) rs9939609 A-allele has been associated with obesity risk. Although the exact mechanisms involved remain unknown, the FTO rs9939609 A-allele has been associated with an impaired postprandial suppression of appetite. Objectives To explore the influence of FTO rs9939609 genotype on fasting and postprandial ...
Background The purpose of this study was to determine physical activity (PA) preferences associated with increases in moderate-to-vigorous physical activity (MVPA) and decrease in sedentary time in Mexican American (MA) women participating in a Promotora (community health worker)-led intervention on the U.S.-Mexico border. Methods Enlace (‘to link’ ...
Background The purpose of this study was to investigate the patterns of objectively measured sedentary behaviour in adults with intellectual disabilities. Methods Baseline accelerometer data were pooled from two randomized controlled trials of lifestyle behaviour change programmes for adults with intellectual disabilities. Patterns of sedentary behaviours were computed including total ...
Background Rapid change in the commercial market can threaten consistency of activity data comparisons as devices are superseded. Purpose: To determine the level of agreement between two generations of Fitbit™ device for step count and activity level in a free-living environment. Methods Thirty-seven healthy participants (17 women, 20 men; M ± SD: age 34 ± 8 ...
Background Overall time spent in moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior are both correlated in couples. Knowledge about the nature and psychosocial correlates of such dyadic covariation could inform important avenues for physical activity promotion. Purpose The present study investigates hour-by-hour covariation between partners (i.e., synchrony) in ...
Abstract Objectives: To examine the differences in serum leptin levels and other relevant factors between male methamphetamine (METH) abusers during early abstinence and healthy controls. Methods: Fifty-five male METH abusers less than 2 weeks after quitting and 50 male healthy controls were enrolled. Abstinence was confirmed by daily negative urine drug screening ...